#TRANSLUCENT CELLS CONTAINING KERATIN SKIN#

These are stratified squamous epithelial cells that are shed from the surface of the skin daily. Cell that contain keratin are known as keratinocytes.

The epidermis is made up a variety of cell types. Stratum corneum - dead, non-nucleated cells filled with keratine filaments Stratum lucidum - present only in palms and soles translucent cells filled with keratine filaments Stratum granulosum - flattened, polygonal pycnotic cells that contain keratohyaline granules, Odland bodies Stratum spinosum - contains post-mitotic cells from stratum basale that contain keratine fibrils melanosomes, Langerhans cells Stratum basale (germinativum) - stem cells constantly undergoing mitosis, regenerate other layers Langerhans cells - antigen presenting cells Melanocytes - synthesise melanin that gives color to the skin and protects it from ultraviolet radiation Keratinocytes - squamous epithelial cells that originate from basal stem cells continuously mature from basal to corneum layer and desquamate Of note, the stratum lucidum is absent from hirsute skin but present in glabrous skin. The thick, hairless skin in the palms and soles are therefore called glabrous skin, while skin elsewhere is referred to as hirsute (hairy) skin. Furthermore, there are no sebaceous glands or hair follicles located in the skin in the palms and soles, while those structures are found in other areas of the body. The epidermis is significantly thicker in the regions of the palms and soles, when compared to other areas of the body. It also develops clefts and ridges that are perceived on the thickened areas of skin as imprints (i.e. The daughter cells ascend the epidermal layers, while undergoing morphological changes throughout its journey. The basal layer undergoes continuous mitosis throughout life. The basal, prickle cell and granular layers are metabolically active regions of the epidermis. The prickle cell and basal layers are collectively referred to as the Malpighian layer. Protection, thermoregulation, detecting sensory stimuliĭesquamation imbalance, psoriasis, albinism, melanoma, squamous cells carcinoma Hypodermis - deepest layer with loose connective and adipose tissue The largest bodily organ that covers and protects the external surface of the body. Key facts about the skin histology Definition The surface of the skin is a parameter that is often used in determining the therapeutic dose for various medications. Owing to variations in height and weight, the surface area of the skin may vary based on these parameters.

It is comprised of three major layers: epidermis, dermis and hypodermis, which contain certain sublayers. The organ constitutes almost 8-20% of body mass and has a surface area of approximately 1.6 to 1.8 m2, in an adult. Undoubtedly, the skin is the largest organ in the human body literally covering you from head to toe. This article will describe the anatomy and histology of the skin.

Translucent cells containing keratin